MITOCHONDRIA-MEDITATED PATHWAYS OF ORGAN FAILURE UPON INFLAMMATION

Mitochondria-meditated pathways of organ failure upon inflammation

Liver failure induced by systemic inflammatory response (SIRS) is often associated with mitochondrial dysfunction but the mechanism linking SIRS and mitochondria-mediated liver failure is still a matter of discussion.Current hypotheses suggest that causative events could be a drop in ATP synthesis, opening of mitochondrial permeability transition p

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